Source : wikipedia
Hypoallergenic qualities of the Siberian coat have been noted and commented on for almost ten years. While there is little scientific evidence, breeders and pet owners claim that Siberians can be safe for many allergy sufferers. Since females of all feline breeds produce lower levels of Fel d1, breeders often suggest that allergic families adopt female cats. Allergy sufferers are advised to check their reactivity directly with the parent cats from whom they plan to adopt a kitten. Many people believe that the breed produces less Fel d1, the primary allergen present on cats.
A not-for-profit association of breeders, (Siberian Research Inc), was founded in 2005 to study allergen levels and genetic diseases in the Siberian breed. As of March 2010, fur and saliva samples from over 300 Siberians have been submitted for analysis, many directly from a veterinarian. Salivary Fel d1 allergen levels in Siberians ranged from 0.08-27 mcg per ml of saliva, while fur levels ranged from 5-1300 mcg. The high-end of these ranges is consistent with results from prior studies, though the low end is below expected results.
All Siberians tested were found to produce some Fel d1, with the highest levels being found in Siberians that have silver coloured fur. About half of Siberians were found to have Fel d1 levels lower than other breeds, while under twenty percent would be considered very low. Within the low group, males and females had comparable allergen levels.